Joana Magalhaes



I did my bachelor in Biochemistry between 2008 and 2011 at Faculty of Sciences of the University of Lisbon and by the end of 2013 I finished my master’s degree in Medicinal Chemistry at the Faculty of Pharmacy of Lisbon.

Concerning my research experience, as a student of Biochemistry, I did two internships. In the first I worked in a clinical analysis laboratory and performed the most common assays used in blood and urine analyses. In the second, I did purification of enzymes and activity assays and also proteins crystallography at Instituto de Tecnologia Química e Biológica.

In the scope of my master’s thesis I developed new synthetic procedures to obtain new antimalarial compounds and studied their metabolic stability using HPLC. Afterwards, I worked as a research fellow at Faculty of Pharmacy of the University of Lisbon where I kept developing the Project that I started in my master. This way, I synthesized a small library of compounds and analyzed their metabolic profiles using techniques like HPLC and LC‐MS/MS and also permeability studies in CACO‐2 cell line. Moreover, I also performed some formulation assays in order to improve the physical properties of the synthesized compounds for in vivo studies.

This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska Curie grant agreement No  642620
European Union